server {
        listen 80;
        server_name DOMAIN_HERE;

        access_log /var/log/nginx/access.DOMAIN_HERE.log;

        gzip on;
        gzip_disable msie6; # disable gzip for IE6
        gzip_static on;
        gzip_comp_level 9; # highest level of compression
        gzip_proxied any;
        gzip_types text/plain text/css application/x-javascript text/xml application/xml application/xml+rss text/javascript;

        proxy_redirect off;
        proxy_set_header Host $host;
        proxy_set_header X-Real-IP $remote_addr;
        proxy_set_header X-Forwarded-For $proxy_add_x_forwarded_for;
        proxy_pass_header Set-Cookie;

        root /PATH/TO/WORDPRESS;

        # default location, used for the basic proxying
        location / {
                # if we're requesting a file and it exists, return it and bail out
                if (-f $request_filename) {
                        break;
                }

                client_max_body_size 2m; # increase this to increase file upload size
                proxy_pass http://localhost:APACHE_PORT;
        }

        # handle uploaded files
        location ~* files/ {
                root /PATH/TO/WORDPRESS/blogs.dir/BLOG_ID/;
        }

        # handle static files
        location ~* \.(jpg|png|gif|jpeg|js|css|mp3|wav|swf|mov|doc|pdf|xls|ppt|docx|pptx|xlsx|txt|htm|html)$ {
                # if the static file doesn't exist, handle it with Apache
                if (!-f $request_filename) {
                        break;
                        proxy_pass  http://localhost:APACHE_PORT;
                }
        }

        set $supercache_file "";
        set $supercache_uri $request_uri;

        # reset cache URI if POSTing - bypass cache
        if ($request_method = POST) {
                set $supercache_uri "";
        }

        # bypass cache if there's a query string
        if ($query_string) {
                set $supercache_uri "";
        }

        # bypass cache if one of the cookies below is set
        if ($http_cookie ~* "comment_author_|wordpress|wp-postpass_") {
                set $supercache_uri "";
        }

        # if the URI is still set (rules above don't trigger) then set our file location!
        if ($supercache_uri ~ ^(.+)$) {
                set $supercache_file /wp-content/cache/supercache/$http_host$1index.html;
        }

        # rewrite the request to the cached HTML file
        if (-f $document_root$supercache_file) {
                rewrite ^(.*)$ $supercache_file break;
        }

        # if file exists, return it - will bypass back to Apache if not
        if (-f $request_filename) {
                break;
        }

}